The Chicago White Sox get set to host the Minnesota Twins at Guaranteed Rate Field on Tuesday evening. It’s time to continue our MLB odds series and make a Twins-White Sox prediction and pick.

This series will finally get underway as Monday's opener was postponed due to weather. Minnesota will look to build on a good weekend that saw them win a couple against the Cleveland Indians. Chicago, on the other hand, has lost six of its last eight games to date. The White Sox still hold a multi-game lead in the AL Central entering play, though.

Here’s how sportsbooks have set the Twins-White Sox odds.

MLB Odds: Twins-White Sox Odds

Minnesota Twins +1.5 (-165)

Chicago White Sox -1.5 (+145)

Over 8.5 Runs (-107)

Under 8.5 Runs (-113)

Why The Twins Could Cover The Spread

Although the Twins got off to a horrible start this season and may not be able to recover at all, they have been playing very well of late. The Twins have won seven of their last nine games and took their most recent series against the Indians to gain ground in the division. Minnesota is now tied with the Kansas City Royals and Detroit Tigers at the bottom of the division and will have to make up 11.5 games to catch the White Sox.

Minnesota's offensive production has been solid. The Twins own the eighth-best team batting average at .246. They are currently averaging 4.72 runs per road game and 4.66 runs per game overall. With guys like Nelson Cruz anchoring this lineup, they have the power to slug it out with pretty much anyone. It is the pitching and defense that has hindered this club with their 5.29 runs allowed per game, which is 28th in the majors.

The Twins will turn to veteran right-hander Kenta Maeda for the series opener. Maeda has had his fair share of struggles this season with a 3-2 record and 4.85 ERA through 11 starts. He has made two promising starts since returning from arm soreness. The right-hander is 1-0 with three earned runs and 11 strikeouts over 9 1/3 innings of work during the recent stretch.

Why The White Sox Could Cover The Spread

The White Sox are coming down to earth in a big way. Their record has fallen to 45-31 and their hot start is to thank for the fact that they still hold a 2.5-game lead over the Indians in the division. The White Sox did win their series finale with the Seattle Mariners by a score of 7-5 and will hope to bring some of that momentum into this series.

The White Sox have one of the best lineups in all of baseball despite a plethora of key injuries. Chicago has the fifth-best team batting average at .249. Shortstop Tim Anderson is putting together another impressive season for the Sox with a .295 batting average. The White Sox are averaging 4.82 runs per game, which is the ninth-best mark in the league. Their pitching staff has been phenomenal this season, allowing just 3.29 runs per game at home.

Chicago will turn to right-hander Lucas Giolito for the series opener. Giolito is putting together another solid season with a 5-5 record and 3.80 ERA through 15 starts. He has heavily depended on the punch-out with 110 strikeouts through 87 2/3 innings of work. The right-hander has been especially dominant over his last seven starts with a 2.74 ERA and 60 strikeouts through 46 innings.

Final Twins-White Sox Prediction & Pick

While Minnesota is playing well and has momentum coming in, I think that the off day benefits the White Sox more here. Chicago has been struggling, and a lot of that is because of their current health. Any day off is a good one for this club, so I expect them to come out hot at home against a struggling arm in Kenta Maeda. Maeda will be pitching on unusually long rest, which can have a negative effect on many pitchers. Look for the White Sox to turn the tides in this series, starting with this game.

FINAL PICK: Chicago White Sox ML (-131)