The Kansas City Chiefs will look to bounce back from Sunday night’s loss to the Baltimore Ravens when they host the LA Chargers this week. With that being said, it’s time to continue our NFL odds series and make a Chargers-Chiefs prediction and pick.

In both games of the season thus far, Kansas City has scored over 30 points and 400 total yards. As for the Chargers, they are off to a disappointing 0-2 start to their 2021 campaign.

Here’s how the bookmakers have set the odds:

NFL Odds: Chargers-Chiefs Odds

Chargers: +6.5 (-104)
Chiefs: -6.5 (-116)
Over: 56 (-110)
Under: 56 (-110)

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Why The Chargers Could Cover the Spread

In his first NFL action in Week 2 of the 2020 season, Chargers quarterback Justin Herbert almost knocked off Kansas City. They lost 23-20 at home. This game set the stage for a surprisingly competitive Los Angeles team under the rookie quarterback. In last week’s game, Herbert threw for 338 yards and one touchdown against the Cowboys. He also threw two interceptions and had a QBR of 34.1. Overall, the Chargers did not play well as a unit in their home opener. They gave up 419 total yards of offense and were penalized 12 times for 99 yards. Los Angeles is desperate for a win, which will be a motivating factor for them in this matchup.
As excited as this Chargers offense was to begin the season, they have only scored 17 or less in two games. However, wide receiver Keenan Allen has been off to a good start, totaling 100+ yards in both games. The Chiefs allowed Lamar Jackson to throw for 230 yards through the air, so it seems as though Herbert will be targeting Keenan Allen a lot on Sunday. The Chargers were 5-3 against the spread as an away team last year.

Why The Chiefs Could Cover the Spread

Kansas City lost a very close game against Baltimore on the road. The Chiefs were driving the field when suddenly running back Clyde Edwards-Helaire fumbled the ball in opponent territory. Kansas City gave up 481 total yards of offense and allowed the Ravens to convert over 50% of plays on 3rd down. This resulted in a 36-35 loss, yet the Chiefs get to return home this week, where they went 6-2 last year.

If Kansas City continues to struggle on defense in Week 3 and the game turns into a shootout, Patrick Mahomes and company will have the edge here. Mahomes now has 680 passing yards and six touchdowns against just one interception in two games while completing 76.1 percent of his passes. Also, the Chiefs running backs will have a solid day on the ground as LA’s defense allowed Dallas to produce 198 rushing yards and two touchdowns.

Final Chargers-Chiefs Prediction & Pick

Facing Patrick Mahomes and the Chiefs’ dominant offense early in the season won’t favor the Chargers’ new-look defense. Andy Reid will implement a game plan that will allow Mahomes to sling the ball all over the field. The Chiefs will be fired up after losing last week’s game and win this one by a touchdown in this exciting, high-scoring matchup.

Final Pick: Kansas City -6.5