The Houston Texans will be looking to get back on track after suffering an upset loss at the hands of the Minnesota Vikings in Week 3, and the good news is that they have a Week 4 contest against the winless Jacksonville Jaguars on their slate. The bad news is that they will be without star running back Joe Mixon for the second straight week.

Mixon picked up an ankle injury back in the Texans Week 2 win over the Chicago Bears, and while he was able to finish that game out, he didn't suit up against the Vikings. While Mixon was considered a game-time decision for this contest against the Jaguars, he has been ruled out for the game with Houston opting to play it safe with the talented running back.

Texans will be without Joe Mixon for second straight week

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While Mixon labored through the Texans Week 2 action, he enjoyed a strong start to his career with his new squad back in Week 1 when he racked up 178 total yards and a touchdown in their win against the Indianapolis Colts. Houston has a plethora of weapons on offense, but if Mixon can continue to produce at that incredibly high level when he eventually returns to action, that will make them an even tougher team to beat.

With Mixon officially out, that means Cam Akers would get the nod as the team's starting running back for the second straight week, as Dameon Pierce has also already been ruled out for this game with a hamstring injury. This is certainly a tough blow for the Texans, but considering how bad the Jaguars have been early on this season, they should be able to coast to victory, even without both of their top two running backs being on the field for them.