Manchester United hosted Atletico Madrid for the second leg of their Champions League Round of 16 battle. The two sides entered play even at 1-1, but United failed to find the back of the net and fell to a 1-0 defeat at Old Trafford. With United now out of the Champions League, their hopes for winning a trophy this year are up, marking another disastrous season for the English giants. With Atletico pushing ahead on the back of Renan Lodi's 41st-minute goal, United will hang their heads as they have once again been bounced from the competition.

Naturally, Twitter had a field day at the expense of United, with the world of football fans collectively rejoicing in the Red Devils' defeat. Here are some of the best Twitter reactions to Manchester United's let-down performance.

https://twitter.com/HalaMadridxtr/status/1503849605158612999

Harry Maguire had yet another dreadful performance on Tuesday, and fans were quick to lambaste him in the wake of the defeat.

Manchester United are no longer the giants they once were, and one fan thinks that calling them finished is a gross understatement.

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The trophy-less streak continues for United, who have yet to earn silverware in five years, a historically bad drought for the club which is used to frequent success in all competitions.

When you consider just how much the club has spent in order to achieve success, the results are flat-out embarrassing.

Of all the confusing moments we've seen out of Maguire, just about no one could understand what he was doing in this play, during which he collided heads with Cristiano Ronaldo for seemingly no reason.

Talk about bowing out with class. Not only were United humbled by Atletico Madrid, but Red Devils fans could also be seen throwing drinks at Madrid skipper Diego Simeone as he exited the pitch.

Overall, a disastrous evening in Manchester.