UFC Vegas 36 is set to begin with an early start time. The main card kicks off at 4 pm eastern on ESPN+ and has a main event with major implications. Derek Brunson and Darren Till headline the evening with a massive Middleweight bout. It’s time to continue our UFC odds series, with a Derek Brunson-Darren Till prediction and pick.

Derek Brunson is a dangerous striker who is currently on a four-fight win streak. He’s currently ranked fifth in the Middleweight division and a victory on Saturday night puts him closer to a title shot.

Darren Till is also a prolific striker, but he has been struggling as of late. He’s gone 2-3 in his last five fights, suffering all three of his career losses during this stretch. He hopes to get back in the win column at UFC Vegas 36 and remain in the top 10.

Here’s how the sportsbooks have set the odds for the main event.

UFC Vegas 36 odds: Derek Brunson-Darren Till odds

Derek Brunson (+135)

Darren Till (-155)

Over 3.5 rounds (-105)

Under 3.5 rounds (-125)

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How Derek Brunson wins the fight

Anytime Brunson enters the octagon it’s must-watch television. He’s a phenomenal athlete that’s dangerous on his feet, as 11 of his 22 wins have come via KO/TKO. Brunson has an underrated ground game as well. He doesn’t use it often, but he’s able to hold his own whenever the fight goes to the mat. Even so, look for Brunson to stand and bang as this matchup is right in his wheelhouse.

He enters this UFC matchup with a slight height and reach advantage. The jab will be his best friend, but Brunson should include some leg kicks as well. Patience is the key to victory here, as Derek Brunson should take his time and pick his opponent apart from a distance. If he can do that, Till should open up and Brunson can finish him off with a knockout.

How Darren Till wins the fight

“The Gorilla” Darren Till hasn’t quite been the same since losing his title shot to Tyron Woodley in 2018. He’s hit a string of bad luck, suffering losses from Jorge Masvidal and Robert Whittaker. This is Till’s first appearance since July 2020 and he needs a win to remain amongst the UFC’s best.

For that reason, Till is likely to come out aggressive. He won’t be looking for any takedowns, as keeping it on the feet gives him his best chances. Getting inside of his opponent’s guard is the best strategy in this Middleweight matchup. Look for Darren Till to push the pace as he’ll attempt to control the cage and put his opponent’s back against the fence. If he can do that, Till’s chances to win improve greatly.

Derek Brunson-Darren Till prediction & pick

This UFC fight has the makings to be an all-out war. Neither of these guys are likely to take it to the ground. With both Brunson and Till looking to stand and bang, this fight has the potential to be the fight of the year. Brunson will keep his distance while Till will keep it close. This fight can end at any moment, so whoever sticks to their game plan should come out with a win.

FINAL DEREK BRUNSON-DARREN TILL PICK: Derek Brunson wins via KO/TKO in Round 3