Tight end C.J. Uzomah of the Cincinnati Bengals was carted off on Thursday in their game Cleveland Browns after suffering a serious leg injury.

Uzomah went down and quickly favored his lower right leg after catching a five-yard pass from rookie quarterback Joe Burrow at the 8:14 mark of the fourth quarter. The 27-year-old was carted off the field and ruled out of the game with an Achilles injury. The Bengals lost the game, 35-30.

“The injury to C.J. Uzomah I think is significant,” NFL Network analyst Troy Aikman said during the broadcast, per Dave Clark of the Cincinatti Enquirer. “You're talking about a guy in Joe Burrow who – half of his completions last year went to inside receivers. … He likes utilizing those guys. And he's had a nice little development going with C.J. Uzomah. Big target. Him not in this game any longer is significant.”

Uzomah was having a great game prior to the injury. The tight end left the game with four catches on six targets for 52 yards and one touchdown — Burrow's first passing touchdown of his career in the pros.

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Though the Bengals haven't released a timeline of Uzomah's return, Achilles' injuries have been tagged as the kiss of death in most sports leagues. As such, it usually takes one full season for athletes to heal up and get in shape.

Together with second-year man Drew Sample, Uzomah entered the brand new season as the Bengals' top tight ends. This was after one-time Pro Bowl Tyler Eifert left in free agency.