The Indianapolis Colts and the Baltimore Ravens will battle it out in primetime on Monday Night Football. It’s time to continue our NFL odds series and make a Colts-Ravens prediction and pick.

Both of these teams are fighting to keep pace in their respective divisions, but their stories are very different. The Colts have been ravaged by injury to start the year, and they’ve only earned themselves a 1-3 record over the first month of play. Luckily for Indianapolis, the division-leading Tennessee Titans are only 2-2. A first-place finish in the AFC South isn’t out of the question. Baltimore also suffered a rash of injuries in the early going, but they’ve bounced back nicely. After a tough Week 1 loss to the Las Vegas Raiders, the Ravens won three straight games. This is also Baltimore’s third primetime appearance in five weeks, so they’re certainly getting used to the spotlight.

Here’s how the bookmakers have set the lines for Monday’s game.

NFL Odds: Colts-Ravens Odds

Indianapolis Colts +7 (-110)

Baltimore Ravens -7 (-110)

Over 46 points (-110)

Under 46 points (-110)

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Why The Colts Can Cover The Spread

One thing that has stuck with Indianapolis from last season is their solid defense. The unit has regressed some from 2020, but they’re still much better than most people give them credit for, especially against the run. The Colts have only allowed one 100-yard rusher on the season, and that was Derrick Henry. The last time that these two teams faced each other, Indianapolis held Lamar Jackson to only 58 yards rushing while also holding every single running back on the Ravens to less than 30 yards on the ground. This isn’t a particularly good matchup for Baltimore’s famed ground game.

The Ravens are known for running the football, but it’s possible they’ll be forced to go to the air more than they’d like to in this one. That’s even better news for the Colts, as they’ve been a pretty solid pass defense all season. Indy is yet to allow a 300-yard day to a passer, and the only quarterbacks to surpass 200 yards against them were Matthew Stafford and Russell Wilson. Lamar Jackson is nowhere near the caliber of passer that those two are, so it’s fair to expect a good defensive showing all around from the Colts.

Why The Ravens Can Cover The Spread

This may not be a great matchup for the Baltimore offense, but the same can be said for the Colts’ offensive unit. The Ravens have allowed only 24 points over their last two contests, and they consistently pressured the quarterback in both of those wins. Colts quarterback Carson Wentz happens to be one of the worst signal-callers in the NFL when he’s under pressure. Baltimore should get after Wentz and shred an offensive line that is nowhere near as good as it used to be.

It’s strange to say this, but the Ravens are actually the healthier team as they head into this game. Six Indianapolis starters have either been limited in practice or missed practice throughout the week, so it’s extremely unlikely that all six of those guys actually take the field on Monday. Right tackle Braden Smith and center Ryan Kelly are among the injured, making things even worse for the Colts offense. Linebacker Darius Leonard and safety Khari Willis are also both questionable, so the defense could be missing a couple of key starters as well.

Final Colts-Ravens Prediction & Pick

The Ravens should win this game, but they aren’t the best pick on the board. The under looks great here as both teams have been stout on defense throughout the season. It doesn’t hurt that the Colts should be missing multiple offensive starters in this game.

FINAL PICK: under 46 points (-110)