The Tennessee Titans will be without a key piece of their offensive attack for Week 12 against the New England Patriots, as head coach Mike Vrabel has officially ruled out wide receiver A.J. Brown due to a chest injury.

Brown suffered this injury during the third quarter of the Titans' Week 11 home loss to the Houston Texans. He took on a hard hit by Texans cornerback Desmond King and wound up not returning to the contest. He finished the game with five receptions for 48 receiving yards, but he also came away from the contest with notable rib and hand injuries.

As later noted by the NFL Network's Ian Rapoport, Brown did have negative X-rays on his ribs, which was a promising sign for his possible availability in the upcoming clash with the Patriots. But in the end, the Titans have now elected to take a conservative route by instead ruling him out, especially after he did not feature in a single scheduled practice session with the team this week.

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Brown has only missed one previous game this season; he was held out of the Titans' Week 4 matchup with the New York Jets due to a hamstring injury.

Titans quarterback Ryan Tannehill sure will have to overcome the odds against the Patriots. He will also not have wideout Julio Jones (hamstring) and running back Derrick Henry (foot) for this contest, as they each are on injured reserve due to their respective injuries.

The Titans currently hold the No. 1 seed in the AFC, but a loss in Week 12 could see them fall a few spots in the conference playoff picture.