UFC 264 is set for Saturday, July 10th. Dustin Poirier and Conor McGregor go head-to-head for the third time to close out their rivalry. Everything is on the line in the main event of the evening. It's time to continue our UFC 264 odds series with a Dustin Poirier-Conor McGregor prediction and pick.

Poirier has all of the confidence in the world right now after defeating McGregor by KO in his last bout. He's gone 4-1 in his last five fights, suffering a loss to Khabib Nurmagomedov, which, everyone loses to him. “The Diamond” has looked stellar since 2017 and looks to have a repeat performance against his nemesis on Saturday night.

McGregor is a superstar that took over the globe after gaining fame in the UFC. After being named the highest-paid athlete in the world, “The Notorious” hopes to get back in the win column in UFC 264. He's 3-2 in his last five fights and hopes to redeem himself after suffering the first KO loss of his career earlier this year.

Here's how the sportsbooks have the UFC 264 odds.

UFC 264 odds: Dustin Poirier-Conor McGregor odds

Dustin Poirier (-125)

Conor McGregor (+105)

Over 1.5 rounds (-205)

Under 1.5 rounds (+165)

How Dustin Poirier wins the fight

Confidence is the biggest key when facing McGregor, and Poirier has a ton of it. He's admitted the first time they fought that McGregor got to his head with the trash talk. That loss may have been the best thing for his career, as Poirier has gone 12-2 since 2015. When Poirier enters the cage focused, he tends to do some damage.

His best bet will be to take McGregor down to the matt. We've seen McGregor struggle on the ground throughout his career, so this is the obvious game plan for anyone fighting “Notorious.” However, Poirier is solid with his stand-up game and beat Conor at his own game back in January. Poirier may go toe-to-toe with McGregor, even though he should take it to the ground. Look for Poirier to use leg kicks and force McGregor into the clinch as soon as possible.

How Conor McGregor wins the fight

The last time Conor McGregor suffered an embarrassing loss then returned for a rematch was against Nate Diaz. That first bout with Diaz looked like McGregor underestimated his opponent and he got caught in a submission. Similar to his last bout against Poirier, McGregor seemed too confident and got caught by Poirier's punching power. We should see a more focused version of “Notorious” as he aims to redeem himself on Saturday night.

Keeping it on the feet is clearly the game plan for McGregor. That's his bread and butter, as he's one of the most prolific kickboxers in the game. He might have a slightly different approach heading into this one after getting caught in the first bout. Even so, we should see the same Conor McGregor we typically see in the octagon. If he can keep his distance and turn this into a kickboxing match, the advantage tilts in McGregor's favor.

Dustin Poirier-Conor McGregor prediction & pick

This is a highly anticipated rematch, as the winner will be deemed the better fighter between the two. The roles may be reversed leading into this matchup, as Poirier is feeling rather confident for this fight. McGregor on the other hand seems to be a bit more calm, relaxed, and most importantly, focused on the bout. If this fight goes beyond the third round, it'll come down to whoever wants it more. However, each of these guys has knockout power and can end the fight at any moment. Look for McGregor to hit Poirier with a big counter to put the rivalry to rest.

FINAL Dustin Poirier-Conor McGregor prediction pick using UFC 264 odds: Conor McGregor wins by KO/TKO in the 2nd round