Chris Flexen takes the mound for the Chicago White Sox as they host the Houston Astros. It's time to continue our MLB odds series with an Astros-White Sox prediction and pick.

Astros-White Sox Projected Starters 

Spencer Arrighetti vs. Chris Flexen

Spencer Arrighetti (3-6) with a 6.37 ERA and 1.71 WHIP

Last Start: In his last start, Arrighetti went just 1.1 innings, giving up five hits, two walks, and three home runs. This would result in seven runs being scored as he took the loss to the Tigers.

2024 Road Splits: On the road this year, Arrighetti has made six starts. He is 2-2 with a 6.39 ERA and a .280 opponent batting average.

Chris Flexen (2-6) with a 5.35 ERA and a 1.40 ERA.

Last Start: Flexen went just 3.1 innings last time out giving up nine hits, two walks, and a home run. This resulted in six runs, with four earned as Flexen took the loss to the Diamondbacks.

2024 Home Splits: Flexen has made eight starts at home this year, going 1-3 with a 5.70 ERA and a .264 opponent batting average.

Here are the MLB Odds, courtesy of FanDuel. 

MLB Odds: Astros-White Sox Odds

Houston Astros: -1.5 (-115)

Moneyline: -184

Chicago White Sox: +1.5 (-104)

Moneyline: +154

Over: 9 (-110)

Under: 9 (-110)

How to Watch Astros vs. White Sox

Time: 2:10 PM ET/ 11:10 AM PT

TV: SCHN/NBCSCA

Stream: fuboTV (Click for free trial)

Why The Astros Will Cover The Spread/Win

The Astros are 14th in the majors in runs scored while sitting first in batting average, 11th in on-base percentage, and sixth in slugging. Kyle Tucker is having a great year. he is hitting .266 on the yeah with a .395 on-base percentage. Tucker has 19 home runs, 40 RBIs, and has scored 42 times. Tucker has also stolen ten bases. Meanwhile. Yordan Alvarez has also been solid. He is hitting .290 on the year with a .362 on-base percentage. He has 14 home runs and 37 RBIs on the year while scoring 40 times. Rounding out the top bats on the year is Jose Altuve. Altuve is hitting .295 on the year with 11 home runs and 29 RBIS. He has also scored 42 times this year, and stolen ten bases.

Alvarez has also been solid in the last week. He is hitting .308 in the last week with a double and a home run. He has four RBIs and two runs scored in the last week. Jose Altuve continues to hit well as well. He is hitting .294 in the last week with a home run and three RBIs. He has scored three times in the last week. Rounding out the top bats in the last week with Alex Bregman. Bregman is hitting .300 in the last week with a triple and an RBI. He has also scored three times.

Current members of the Astors have 70 career at-bats against  Chris Flexen. They have hit .286 against him with a .359 on-base percentage. Yordan Alvarez has been great against Flexen. He is four for 14 with two walks, two home runs and five RBIs. The other player with RBIs against Flexen is Jeremy Pena. Pena is five for 11 with a double and two RBIs.

Why The White Sox Will Cover The Spread/Win

The White Sox are 30th in the majors in runs scored, while sitting 30th in batting average, 30th in on-base percentage, and 30th in slugging. Andrew Vaughn leads the team in RBIs this year. He is hitting .235 with nine home runs and 33 RBIs on the year. He has also scored 26 times. Meanwhile, Paul DeJong has also been solid this year. He is hitting .237 this year with a .285 on-base percentage. He has 14 home runs and 29 RBIs this year while scoring 29 times. Rounding out the top bats on the year is Gavin Sheets. Sheets is hitting .232 on the year with seven home runs and 28 RBIs while scoring 21 times.

Andrew Vaughn has been great in the last week. He is hitting .308 in the last week with two home runs and ten RBIs. He has also scored three times in the last week. Lenyn Sosa has also been solid. He is hitting .316 in the last week with a home run and three RBIs. He has also scored twice. Scoring well is something Luis Robert Jr has done in the last week. He is hitting just .158 but with a .273 on-base percentage. Robert has hit two home runs, both solo home runs. He has also scored four times in the last week. As a team, the White Sox are hitting just .217 in the last week, but do have seven home runs and have scored 21 times.

Final Astros-White Sox Prediction & Pick

The White Sox have been dreadful this year. They have the worst offense in the majors and it does not help when they are not only facing a solid offense, but an offense full of hot bats. Further, the White Sox are sending Chris Flexen to the mound, who has not been good this year. Take the Astros in this one.

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Final Astros-White Sox Prediction & Pick: Astros ML (-184)