Kyle Hendricks will be looking for his first win of the year as the Chicago Cubs host the San Francisco Giants.  It's time to continue our MLB odds series with a Giants-Cubs prediction and pick.

Giants-Cubs Projected Starters 

Undecided vs. Kyle Hendricks

Undecided  (0-0) with a 0.00 ERA …

Last Start:

2024 Road Splits:

Kyle Hendricks (0-4) with an 8.20 ERA and a 1.71 WHIP

Last Start: In his last start, Hendricks went 4.1 innings in relief, giving up just two hits, and no runs. Still, he took the no decision as the Cardinals defeated the Cubs 3-0.

2024 Home Splits: Hendricks has made three starts at home, with six total appearances. He is 0-2 with a 7.36 ERA and an opponent batting average of .351.

Here are the MLB Odds, courtesy of FanDuel. 

MLB Odds: Giants-Cubs Odds

San Francisco Giants: -1.5 (+152)

Moneyline: +102

Chicago Cubs: +1.5 (-184)

Moneyline:-120

Over: 11.5 (+104)

Under: 11.5 (-128)

How to Watch Giants vs. Cubs

Time: 2:20 PM ET/ 11:20 AM PT

Article Continues Below

TV: NBCSBA/MARQ

Stream: fuboTV (Click for free trial)

Why The Giants Will Cover The Spread/Win

The Giants are 13th in the majors in runs scored, while sitting 11th in opponent batting average, eighth in on-base percentage, and 17th in slugging. Thario Estrada has led the way this year. He is hitting .243 on the year with nine home runs and 29 RBIs. He also has 13 doubles and a triple, plus has scored 37 times. Meanwhile, Matt Chapman continues to drive in runs. He is hitting just .230 on the year, but he has a .309 on-base percentage. Chapman has eight home runs and 30 RBIs while scoring 43 times on the year. Also having a good season is Heliot Ramos. Ramos has played in just 36 games this year but is hitting .328 in those games, with no home runs and 31 RBIs.

Ramos has been on fire in the last week. He is hitting .370 in the last week, with three home runs and eight RBIs. He has also scored three times in the last week. Also hitting well in the last week is Jorge Soler. Soler is hitting .412 in the last week with a home run and four RBIs. He has scored seven times in his last six games. Rounding out the hottest bats is Austin Slater. Slater is hitting .429 in the last week, with a home run, four RBIs, and four runs scored.

Current members of the Giants have 76 career at-bats against Kyle Hendricks but have not found much success. They are hitting just .118 against him. Wilmer Flores has the most experience, with three hits in 21 at-bats, with a double and three RBIs. Nick Ahmed is two for 20 but also has three RBIs against Hendricks.

Why The Cubs Will Cover The Spread/Win

The Cubs are 18th in the majors in runs scored, while sitting 26th in batting average, 17th in on-base percentage, and 25th in slugging. Christopher Morel has been great this year. He is hitting just .196 but has a .301 on-base percentage. Morel has 13 home runs, 40 RBIS, and 34 runs scored this year. Ian Happ has also been solid this year. He is hitting .229 with a .340 on-base percentage. He has eight home runs, 36 RBIs and 34 runs scored this year. Leading the team in hitting this year is Mike Tauchman. Tauchman is hitting .259 with a .359 on-base percentage. He has five home runs, and 19 RBIs this year. Tauchman also has 38 runs scored this year.

Ian Happ has also hitting well in the last week. He is hitting .316 in the last week with a .458 on-base percentage. He has two home runs and six RBIs in the last week. He has scored three times as well in the last week. Michael Busch is also having a great week. Busch is hitting .389 in the last week with a .450 on-base percentage. Busch has a home run and three RBIs while scoring twice. Cody Bellinger is not hitting better as of late. he is hitting .250 in the last week with a home run and three RBIs. He has scored four times as well.

Final Giants-Cubs Prediction & Pick

Kyle Hendricks has struggled heavily this year. He did not make a start on May 17th where he gave up eight runs, with even earned, in 4.2 innings of work. Since then, he has appeared in five games, with the Cubs losing all of them. Still, he has been better as of late. In his last three appearances, he has pitched 8.2 innings, giving up six hits, and no runs. Regardless, with Hendricks on the mound, expect plenty of runs to be scored by the Giants in this one. The Cubs will put up runs too though. They have multiple batters hitting well and scoring well.  With that, the best play in this game is on the total. Take the over.

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Final Giants-Cubs Prediction & Pick: Over  11.5 (+104)