JACKSONVILE, FL — The Jacksonville Jaguars kickoff their 25th season in franchise history Sunday afternoon as they host the Kansas City Chiefs at TIAA Bank Field. All eyes will be on 2018 NFL MVP Patrick Mahomes in what is the Jaguars' first home game on Week 1 since the 2011 season. Head coach Doug Marrone is 3-1 for his career in Week 1 matchups but 2-0 with Jacksonville.

Can the Jaguars pull off an upset as home underdogs and go 3-0 under Marrone on Kickoff Weekend?

These two sides matched up in October of 2018 when the Chiefs won, 30-14. Things are a little different this time around, though, with quarterback Nick Foles entering the fold after signing a four-year deal in the offseason. The former Super Bowl champ enters the 2019-20 season with a career QB rating of 88.5, owning the sixth-highest career postseason passer rating in NFL history at 98.8.

“The things I focus on when I play the game are trust, love and caring for the guys around me,” Foles said earlier this summer. “That's something where you can't just make a play and say, ‘It's got to be this way.' That's something that's built over time and we've been building since OTAs.”

All signs point to a competitive Week 1 matchup here. Jacksonville has a +84 scoring margin at home with Marrone at the helm, allowing just 15.3 points per game at TIAA.

Jacksonville is no stranger to the spotlight on Week 1. Last year, they hosted reigning MVP Tom Brady and the New England Patriots in Week 1. The Jaguars won, 31-20, behind four touchdowns from QB Blake Bortles.

This year, it's Mahomes and a potent Chiefs offense. Can Foles step up to the challenge?