Green Bay Packers running back MarShawn Lloyd has had a rookie season marred by injury. Heading into Week 11, Lloyd has suffered another worrying setback.

The running back is dealing with appendicitis and missed Friday's practice, via team reporter Wes Hodkiewicz. Head coach Matt LaFleur will have a further update once Lloyd undergoes treatment.

“Unfortunately, he has appendicitis,” LaFleur said of Lloyd. “It's a shame because he was making progress.”

Lloyd was placed on injured reserve with an ankle injury. Then, he picked up a hamstring ailment. He seemed to be on the path back to playing, getting in limited practices on Wednesday and Thursday. Now, his appendicitis has thrown a wrench into Green Bay's plans.

Article Continues Below
More Green Bay Packers News
Green Bay Packers quarterback Aaron Rodgers (12) and quarterback Jordan Love (10) listen to head coach Matt LaFleur during the fourth quarter of their game Sunday, December 4, 2022 at Soldier Field in Chicago, Ill. The Green Bay Packers beat the Chicago Bears 28-19.
Packers’ Jordan Love gives clear thoughts on Aaron Rodgers signing with SteelersJaren Kawada ·
New York Jets quarterback Aaron Rodgers (8) reacts following a loss to the Pittsburgh Steelers at Acrisure Stadium. Barry Reeger-Imagn Images
When Aaron Rodgers will face Packers, Bears in 2025 NFL seasonJake Faigus ·
Matthew Golden, Packers
Rising Packers rookie turning heads in 2025 OTAsDouglas Fritz ·
Green Bay Packers wide receiver Romeo Doubs (87) is unable to make a reception during the fourth quarter of their game
Matt LaFleur highlights Packers ‘specimen’ with ‘physique’ transformationScotty White ·
Green Bay Packers wide receiver Romeo Doubs (87) makes a catch and runs the ball against the Tennessee Titans during the first half at Nissan Stadium
Packers WR Romeo Doubs gets brutally honest on major ‘regret’Ben Strauss ·
Green Bay Packers wide receiver Matthew Golden is interviewed by the media during rookie minicamp on Friday, May 2, 2025, at Lambeau Field in Green Bay, Wisconsin. The Packers selected Golden with their first round pick in the 2025 NFL Draft.
Packers’ Romeo Doubs stunned by ‘stud’ rookie receiverZachary Weinberger ·

The Packers had activated Lloyd's 21-day practice window. But now, he's looking at another layoff, meaning he could run out of time before his window closes. If that were to happen, Lloyd would need to miss the rest of the season. But Green Bay is talking to the NFL to see if there's a chance Lloyd can still play later in the year, via Rob Demovsky of ESPN.

Even if the league agrees to the Packers' request, Lloyd's rookie season has not panned out how the team has hoped. Not all is lost in the running back room, as Josh Jacobs has gained 762 yards and scored three touchdowns. But Lloyd was expected to be a fiery counterpart and explosive part of Green Bay's run game. Instead, he has gained just 15 yards on six touches.

After what had been a promising week for MarShawn Lloyd has now ended in mystery. Once the Packers have a better understanding of his timeline, they can craft a better injury plan. However, another multi-week absence would spell doom for both Lloyd and Green Bay. Alongside a clean bill of health, the Packers will hope the NFL shows some leniency based on the circumstances around Lloyd's new injury.